Caesalpinia sappan L. (Leguminosae) is found in India, Malaysia, southern China, and tropical Asia, and its heartwood Sappan lignum is used as a red dye. Family Name: Fabaceae (Leguminosae). Common Names: Sappan Wood, Brazilwood Tree, Sappan. Chinese Name: 苏木. by; G. Renu, Sanjana Julias Thilakar, D. Narasimhan, Centre for Floristic Research, Department of Botany, Madras Christian College, Tambaram. (0 ratings).

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Showing 0 caeealpinia 0 comments. The dyeing is achieved by three successive extractions, reducing the amount of water each time. It is also used to cure wounds also with a plaster of macerated leaves and bark, diarrhoea and dysentery and is reported as having antioxidative, anti-inflammatory, hepatoprotective, cytotoxic, hypoglycaemic and xanthine oxidase-inhibitory activities.

Table 1 Microstructure of cancellous bone at the distal part of the left femur. Brazilin selectively disrupts proximal IL-1 receptor signalling complex formation by targeting an IKK-upstream signalling components. Retrieved Jul 6, Brazilin and MTX were dissolved in a small volume of dimethylsulfoxide DMSO and its concentration was adjusted to working concentration with 0. Planta Medica 63 5: Prolonged boiling intensifies the colour of the dye.

Caesalpinia sappan L. | Species | India Biodiversity Portal

Rheumatoid arthritis RA is sappn systemic inflammatory disease of the synovium, cartilage, and bone. Document specific search options Title. There are book citations related to Caesalpinia sappan L.


It also is a good source of firewood. Slivers of heartwood are used for making herbal drinking water in various regions, such as Kerala and Central Java, where it is usually mixed with gingercinnamonand cloves.

Lubrecht and Cramer Ltd. Brazilin from Caesalpinia sappan wood as an anti-acne agent. Chemical shifts are reported in parts per million ppm downfield from those of an internal tetramethylsilane TMS standard. The wood is somewhat lighter in color than Brazilwood and other related trees. By using this site, you agree to the Terms of Use and Privacy Policy. Drugs and experimental animals Brazilin was kept in brown caesa,pinia bottle and a vacuum container.

Biancaea sappan – Wikipedia

We induced the development of chronic inflammation and closely monitored the effects thereof in terms of joint edema, erythema, and immobilization. RA causes persistent pain, stiffness, swelling, deformities, and loss of joint function [ 12 ].

Anti-inflammatory activities of an ethanol extract of Caesalpinia sappan L. Antioxidant activity of Caesalpinia sappan heartwood.

Used part of the plant: Handbook of legumes of world economic importance. Some reports have documented the synthesis of novel cytokines including IL, IL, and RANK ligand in the synovium, which secretes enzymes degrading proteoglycans and collagen, in turn causing bone loss [ 45 ].


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A decoction or infusion of the heartwood is generally considered a strong emmenagogue and astringent. We explored whether brazilin purified from C. Although all of these drugs reduce acute inflammation and pain, they do not change the course of the disease or prevent joint destruction.

The majority of these compounds are transformed into brazilin by heating, in the weak acidic or basic media resulting from the current dye-extraction processes. After the tree is felled the stump sprouts profusely within two weeks. Brazilin exhibits various biological activities including anti-hyperglycemic [ 15 ], anti-hepatotoxic [ 14 ], and anti-inflammatory effects [ 17 ].

This plant has many uses. Li JC, Kaminskas E. Between groups comparisons were performed using the post-hoc Tukey test. National Center for Biotechnology InformationU.

Le monde des teintures naturelles. These results suggest that brazilin derived from the heartwood of C. The heart of the trunk and larger branches only are used for the extraction of the dye.

Abatacept therapy for rheumatoid arthritis in the setting of hepatitis C infection.